Issac is an established variant of Isaac that peaked in 2008 and has grown less common since.
Issac is predominantly a boy name. In 2025 it ranked #915 for boy births in the United States (and #1,874 across all names), given to 258 babies. Issac first appears in 1880 and peaked in 2008 (820 births).
| Year | U.S. births | U.S. + territories | ♀ Rank | ♂ Rank |
|---|---|---|---|---|
| 2025 | 258 | 258 | — | #915 |
| 2024 | 287 | 287 | — | #847 |
| 2023 | 320 | 320 | — | #789 |
| 2022 | 393 | 393 | — | #686 |
| 2021 | 419 | 419 | — | #653 |
| 2020 | 429 | 429 | — | #627 |
| 2019 | 441 | 441 | — | #621 |
| 2018 | 487 | 487 | — | #567 |
| 2017 | 439 | 439 | — | #604 |
| 2016 | 443 | 443 | — | #609 |
| 2015 | 509 | 509 | — | #562 |
| 2014 | 503 | 503 | — | #547 |
| 2013 | 593 | 593 | — | #469 |
| 2012 | 622 | 622 | — | #443 |
| 2011 | 640 | 640 | — | #425 |
| 2010 | 628 | 628 | — | #437 |
| 2009 | 684 | 684 | — | #423 |
| 2008 | 820 | 820 | — | #376 |
| 2007 | 793 | 793 | — | #384 |
| 2006 | 723 | 723 | — | #408 |
| 2005 | 698 | 698 | — | #405 |
| 2004 | 666 | 666 | — | #397 |
| 2003 | 653 | 653 | — | #399 |
| 2002 | 615 | 615 | — | #412 |
| 2001 | 618 | 618 | — | #403 |
| 2000 | 520 | 520 | — | #457 |
| 1999 | 506 | 506 | — | #454 |
| 1998 | 463 | 463 | — | #475 |
| 1997 | 416 | — | — | #499 |
| 1996 | 384 | — | — | #521 |
| 1995 | 319 | — | — | #572 |
| 1994 | 309 | — | — | #588 |
| 1993 | 290 | — | — | #610 |
| 1992 | 254 | — | — | #649 |
| 1991 | 279 | — | — | #610 |
| 1990 | 275 | — | — | #607 |
| 1989 | 202 | — | — | #695 |
| 1988 | 172 | — | — | #716 |
| 1987 | 158 | — | — | #728 |
| 1986 | 174 | — | — | #686 |
| 1985 | 179 | — | — | #657 |
| 1984 | 158 | — | — | #694 |
| 1983 | 213 | — | #9,459 | #592 |
| 1982 | 198 | — | — | #612 |
| 1981 | 197 | — | — | #609 |
| 1980 | 212 | — | #10,964 | #606 |
| 1979 | 193 | — | — | #615 |
| 1978 | 151 | — | — | #682 |
| 1977 | 121 | — | — | #774 |
| 1976 | 152 | — | #8,517 | #684 |
| 1975 | 127 | — | — | #736 |
| 1974 | 141 | — | — | #692 |
| 1973 | 125 | — | — | #721 |
| 1972 | 147 | — | — | #664 |
| 1971 | 100 | — | — | #808 |
| 1970 | 82 | — | — | #893 |
| 1969 | 64 | — | — | #962 |
| 1968 | 57 | — | — | #978 |
| 1967 | 49 | — | — | #1,052 |
| 1966 | 49 | — | — | #1,048 |
| 1965 | 67 | — | — | #907 |
| 1964 | 63 | — | — | #962 |
| 1963 | 67 | — | — | #917 |
| 1962 | 58 | — | — | #1,010 |
| 1961 | 74 | — | — | #892 |
| 1960 | 60 | — | — | #990 |
| 1959 | 65 | — | — | #958 |
| 1958 | 86 | — | — | #812 |
| 1957 | 68 | — | — | #922 |
| 1956 | 72 | — | — | #881 |
| 1955 | 78 | — | — | #834 |
| 1954 | 75 | — | — | #839 |
| 1953 | 89 | — | — | #754 |
| 1952 | 64 | — | — | #882 |
| 1951 | 64 | — | — | #875 |
| 1950 | 70 | — | — | #817 |
| 1949 | 67 | — | — | #840 |
| 1948 | 77 | — | — | #776 |
| 1947 | 66 | — | — | #857 |
| 1946 | 50 | — | — | #947 |
| 1945 | 60 | — | — | #802 |
| 1944 | 59 | — | — | #819 |
| 1943 | 54 | — | — | #909 |
| 1942 | 48 | — | — | #962 |
| 1941 | 52 | — | — | #880 |
| 1940 | 29 | — | — | #1,264 |
| 1939 | 51 | — | — | #864 |
| 1938 | 55 | — | — | #843 |
| 1937 | 51 | — | — | #859 |
| 1936 | 48 | — | — | #887 |
| 1935 | 50 | — | — | #899 |
| 1934 | 47 | — | — | #924 |
| 1933 | 50 | — | — | #879 |
| 1932 | 64 | — | — | #795 |
| 1931 | 40 | — | — | #1,070 |
| 1930 | 45 | — | — | #1,030 |
| 1929 | 61 | — | — | #843 |
| 1928 | 60 | — | — | #858 |
| 1927 | 59 | — | — | #886 |
| 1926 | 48 | — | — | #998 |
| 1925 | 38 | — | — | #1,156 |
| 1924 | 59 | — | — | #911 |
| 1923 | 50 | — | — | #988 |
| 1922 | 56 | — | — | #932 |
| 1921 | 58 | — | — | #927 |
| 1920 | 66 | — | — | #830 |
| 1919 | 59 | — | — | #862 |
| 1918 | 63 | — | — | #829 |
| 1917 | 29 | — | — | #1,282 |
| 1916 | 49 | — | — | #906 |
| 1915 | 42 | — | — | #973 |
| 1914 | 35 | — | — | #943 |
| 1913 | 16 | — | — | #1,350 |
| 1912 | 33 | — | — | #762 |
| 1911 | 25 | — | — | #618 |
| 1910 | 20 | — | — | #667 |
| 1909 | 6 | — | — | #1,370 |
| 1908 | 7 | — | — | #1,162 |
| 1907 | 8 | — | — | #1,045 |
| 1906 | 14 | — | — | #661 |
| 1905 | 8 | — | — | #964 |
| 1904 | 19 | — | — | #501 |
| 1903 | 13 | — | — | #635 |
| 1902 | 16 | — | — | #545 |
| 1901 | 7 | — | — | #899 |
| 1900 | 11 | — | — | #815 |
| 1899 | 8 | — | — | #822 |
| 1898 | 7 | — | — | #935 |
| 1897 | 6 | — | — | #1,009 |
| 1896 | 10 | — | — | #752 |
| 1895 | 11 | — | — | #654 |
| 1894 | 11 | — | — | #652 |
| 1893 | 14 | — | — | #521 |
| 1892 | 13 | — | — | #587 |
| 1891 | 8 | — | — | #734 |
| 1890 | 11 | — | — | #618 |
| 1889 | 8 | — | — | #754 |
| 1888 | 14 | — | — | #539 |
| 1887 | 11 | — | — | #565 |
| 1886 | 14 | — | — | #500 |
| 1885 | 17 | — | — | #450 |
| 1884 | 16 | — | — | #478 |
| 1883 | 13 | — | — | #504 |
| 1882 | 11 | — | — | #590 |
| 1881 | 17 | — | — | #424 |
| 1880 | 16 | — | — | #452 |